Amitriptyline Hydrochloride (Generic Elavil) - Product information and Uses
Amitriptyline Hydrochloride (Generic Elavil) is a tricyclic antidepressant (TCA). It is the most widely used TCA and has at least equal efficacy against depression as the newer class of SSRIs . Besides reducing depressive symptoms, these type of tricyclics also provide relief to migraines, tension headaches, anxiety attacks and some schizophrenic symptoms.
Amitriptyline is used for a number of medical conditions including: depressive disorders, anxiety disorders, attention deficit hyperactivity disorder, migraine prophylaxis, eating disorders, bipolar disorder, post herpetic neuralgia, and insomnia. Amitriptyline is used in ankylosing spondylitis for pain relief. It is also used as a preventive for patients with recurring biliary dyskinesia (sphincter of Oddi dysfunction). Amitriptyline is also used in the treatment of nocturnal enuresis in children.
Amitriptyline may be prescribed for other conditions such as post-traumatic stress disorder (PTSD), chronic pain, tinnitus, chronic cough, carpal tunnel syndrome (CTS), fibromyalgia, vulvodynia, interstitial cystitis, male chronic pelvic pain syndrome, irritable bowel syndrome (IBS), diabetic peripheral neuropathy, neurological pain, laryngeal sensory neuropathy, and painful paresthesias related to multiple sclerosis. Amitriptyline Hydrochloride, was developed under the brand name Elavil, by Merck and approved by the FDA on April 7, 1961, for the treatment of major depression in the United States.
Amitriptyline Hydrochloride - Availability And Packaging
Amitriptyline Hydrochloride is available as Generic Elavil Tablets which is packaged in 10 mg, 25 mg, 75 mg tablets. Amitriptyline Hydrochloride is also available as Tryptomer, Tryptizol, Laroxyl, Sarotex and Lentizol.
Amitriptyline Hydrochloride (Generic Elavil) - Dosage
The recommended starting adult dosage is 50-75 mg/day, preferably taken at bedtime. The dosage is increased by 25-50 mg weekly, depending on tolerability, to a maximum of 150-200 mg/day.
Generic Elavil may be taken in divided doses but a large portion of the total dosage has to be taken at bedtime to minimize daytime sedation. Lower dosages are required for pain relief.
Side Effects of Amitriptyline Hydrochloride (Generic Elavil)
The two most commonly occuring side effects of amitriptyline are drowsiness and a dry mouth. Other common side effects include weight gain, changes in appetite, muscle stiffness, nausea, constipation, nervousness, dizziness, blurred vision, urinary retention, insomnia and changes in sexual function.
Some rare side effects include seizures, tinnitus, hypotension, mania, psychosis, sleep paralysis, hypnagogia, hypnopompia, heart block, arrhythmias, lip and mouth ulcers, extrapyramidal symptoms, depression, tingling pain or numbness in the feet or hands, yellowing of the eyes or skin, pain or difficulty passing urine, confusion, abnormal production of milk in females, breast enlargement in both males and females, fever with increased sweating, and suicidal thoughts.
Considerable portions of the text here is from http://en.wikipedia.org/wiki/Amitriptyline and is reproduced here under the Creative Commons Attribution-ShareAlike License