Atorvastatin Calcium (Lipitor Tablets) - Uses, Dosage and Side Effects

Atorvastatin , sold by Pfizer under the trade name Lipitor, is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body. Atorvastatin calcium tablets are marketed by Pfizer under the trade name Lipitor, in tablets form for oral administration.
Atorvastatin is used for the treatment of dyslipidemia and the prevention of cardiovascular disease.

Atorvastatin Calcium - Availability And Packaging

Atorvastatin Calcium is available as Generic Lipitor Tablets (Atorlip) which is packaged in 5 mg, 10 mg and 20 mg oral tablets.

Atorvastatin (Lipitor) - Contraindications

Atorvastatin is contraindicated in the following cases:

  • Active liver disease: cholestasis, hepatic encephalopathy, hepatitis, and jaundice
  • Unexplained elevations in AST or ALT levels
  • Pregnancy
  • Breastfeeding

Precaution must be taken when treating with Atorvastatin Calcium, because rarely it may lead to rhabdomyolysis, it may be very serious leading to acute renal failure due to myoglobinuria. If rhabdomyolysis is suspected or diagnosed, atorvastatin therapy should be discontinued immediately.
Atorvastatin is absolutely contraindicated in pregnancy, it is likely to cause harm to fetal development because of the importance of cholesterol and various products in the cholesterol biosynthesis pathway for fetal development, including steroid synthesis and cell membrane production

Side Effects of Atorvastatin Calcium (Lipitor Tablets)

The most commonly occurring side effects of Atorvastatin include:

  • Weakness
  • Insomnia and dizziness
  • Chest pain and peripheral edema
  • Rash
  • Abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea
  • Urinary tract infection
  • Arthralgia, myalgia, back pain, arthritis
  • Sinusitis, pharyngitis, bronchitis, rhinitis
  • Infection, flu-like syndrome, allergic reaction

Atorvastatin Calcium (Lipitor Tablets) - Dosage

The recommended starting dose of Lipitor is 10 or 20 mg once daily. It is recommended to take the dose of Lipitor at the same time each day.

Additional Information

Additional Info: Prescribing Information



Considerable portions of the text here is from http://en.wikipedia.org/wiki/Atorvastatin and is reproduced here under the Creative Commons Attribution-ShareAlike License