Fluticasone Propionate (Flutivate) - Product information and Uses

Fluticasone propionate is a synthetic corticosteroid derived from fluticasone used to treat asthma and allergic rhinitis (hay fever). It is also used to treat eosinophilic esophagitis. It is also available as Cutivate or Flutivate Cream for the treatment of eczema and psoriasis. Flutivate Cream may be used with caution in pediatric patients 3 months of age or older.

Fluticasone Propionate (Flutivate) - Availability And Packaging

Fluticasone Propionate is available as a cream Flutivate Cream which is packaged in 20g tubes. GlaxoSmithKline currently markets fluticasone propionate as Flovent and Flixotide for asthma, and as Flonase Flixonase for allergic rhinitis (hay fever), as well as a combination of fluticasone and salmeterol as Advair or Seretide.

Side Effects of Fluticasone Propionate

The topical version of Fluticasone Propionate has been associated with burning, stinging, skin irritation, blisters, dryness, skin infection, infected eczema, viral warts, impetigo, atopic dermatitis, pruritus, exacerbation of pruritus, exacerbation of eczema, erythema, and folliculitis.
Side effects associated with the nostril spray version include headache, throat infection, nasal irritation, sneezing, cough, nausea, vomiting, nosebleeds, skin rash, itching, facial swelling, and anaphylaxis. It has also been associated with growth suppression in children.

Fluticasone Propionate (Flutivate) - Contraindications

Flutivate Cream is contraindicated in patients that have hypersensitivity to Fluticasone Propionate or any of the inactive components in the preparation.

Precautions to be taken when using Fluticasone Propionate (Flutivate)

Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal from treatment. Signs of Cushing's syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on treatment.
Patients applying a potent topical steroid to a large surface area or to areas under occlusion have to be periodically evaluated for evidence of HPA axis suppression. Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios.
The treated skin area should not be bandaged or otherwise covered or wrapped so as to be occlusive unless directed by the physician. Patients should report to their physician any signs of local adverse reactions. This medication should not be used on the face, underarms, or groin areas unless directed by a physician.
Flutivate Cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. In case of nursing mothers use of Flutivate Cream is not recommended as Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects .

Fluticasone Propionate (Flutivate) - Dosage

Apply a thin film of Flutivate Cream to the affected skin areas once or twice daily. Rub in gently.

Overdosage of Fluticasone Propionate (Flutivate)

Topically applied Flutivate Cream can be absorbed in sufficient amounts to produce systemic effects

Additional Information

Additional Info: Prescribing Information