Furosemide Tablets (Lasix) - Uses, Dosage and Side Effects

Furosemide is a loop diuretic used in the treatment of congestive heart failure and edema. It is manufactured and marketed under the brand name Lasix by Sanofi-Aventis.
Furosemide is primarily used for the treatment of two conditions: hypertension and edema. It is the first line agent in most people with edema due to congestive heart failure. Edema is associated with heart failure, hepatic cirrhosis, renal impairment, nephrotic syndrome. Lasix is also used adjunct in cerebral/pulmonary edema where rapid diuresis is required. Furosemide tablets are also sometimes used in the management of severe hypercalcemia in combination with adequate rehydration.
It has also been used to prevent Thoroughbred and Standardbred race horses from bleeding through the nose during races. Along with some other diuretics, furosemide is also included on the World Anti-Doping Agency's banned drug list due to its alleged use as a masking agent for other drugs.

Side Effects of Furosemide Tablets (Lasix)

Lasix Tablets can cause dehydration and electrolyte imbalance, including loss of potassium, calcium, sodium, and magnesium. It is especially important to prevent potassium loss. Excessive use of furosemide will most likely lead to a metabolic alkalosis due to hypochloremia and hypokalemia.
Furosemide should be used with caution when combined with corticosteroids (as this increases the risk of electrolyte imbalance), aminoglycoside antibiotics (increases risk of kidney or ear damage), and trimethoprim sulfa (causes decreased platelet count).It is adsvisable not to use Lasix tablets during pregnancy.

Furosemide Tablets (Lasix) - Contraindications

Furosemide has potential interactions with the following medications:

  • Aminoglycoside antibiotics such as gentamicin
  • Aspirin and other salicylates
  • Other diuretics (e.g. ethacrynic acid, hydrochlorothiazide)
  • Indomethacin
  • Lithium
  • Synergistic effects with other antihypertensives (e.g. doxazosin)
  • Sucralfate


Furosemide Tablets (Lasix) - Dosage

The usual initial dose of Lasix is 60 to 80 mg given as a single dose. If required the same dose can be repeated six to eight hours later. The individually determined single dose can be given once or twice a day.
Treatment of Edema may be efficiently and safely caried out by giving Lasix on 2 to 4 consecutive days each week.

Overdosage and Overdose Symptoms of Lasix Tablets (Furosemide)

Overdose of Furosemide may lead to dehydration, change in drinking patterns and urination, seizures, GI problems, kidney damage, lethargy, collapse, and coma.

Furosemide (Lasix Tablets) - Availability And Packaging

Furosemide is available as Lasix Tablets which is packaged as 40 mg Pills.

Additional Information

Additional Info: Prescribing Information

Considerable portions of the text here is from http://en.wikipedia.org/wiki/Furosemide and is reproduced here under the Creative Commons Attribution-ShareAlike License