Lansoprazole (Generic Prevacid) - Product information and Uses

Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid. It was first approved by the U.S. Food and Drug Administration (FDA) in 1995.
The mean plasma elimination half-life is 1.5 hours, and the effects of the medicine lasts for over 24 hours after it has been used for 1 day or more. Lansoprazole is indicated for Treatment of ulcers of the stomach and duodenum, and NSAID-induced ulcers, Treatment of gastroesophageal reflux disease (GERD) (also known as acid reflux disease),Treatment of Zollinger-Ellison Syndrome, Adjunctive treatment of Helicobacter pylori infection, alongside antibiotics.

Lansoprazole (Generic Prevacid) - Availability And Packaging

Lansoprazole is available as Generic Prevacid Capsules (Lanzol Capsules) which is packaged in 15 mg and 30 mg capsules. It is manufactured by a number of companies worldwide under several brand names that include Prevacid, Lanzol, Helicid, Zoton, Inhibitol, Monolitum.

Side Effects of Lansoprazole (Generic Prevacid)

The commonly occuring Side Effects of Lansoprazole are dry mouth, insomnia, drowsiness, blurred vision, rash, pruritus Rarely and very rarely occuring side effects are taste disturbance, liver dysfunction, peripheral oedema, hypersensitivity reactions (including bronchospasm, urinary, angioedema, anaphylaxis), photosensitivity, fever, sweating, depression, interstitial nephritis, blood disorders (including leukopenia, leukocytosis, pancytopenia, thrombocytopenia), arthralgia, myalgia, skin reactions including (erythroderma Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous eruption).
Severe side effects include Gastro-intestinal disturbances (such as nausea 1.3%, abdominal pain 2.1%, diarrhea 3.8%).
Proton-pump inhibitors may be associated with a greater risk of hip fractures, Clostridium difficile-associated diarrhea. Patients are frequently administered the drugs in intensive care as a protective measure against ulcers, but this use is also associated with a 30% increase in occurrence of pneumonia.

Lansoprazole (Generic Prevacid) - Dosage

The recommended dosages to treat various indications are given below:
Duodenal ulcer:
30 mg daily for 4-8 weeks then 15 mg for maintenance dose.
Benign gastric ulcer:
30 mg daily for 8 weeks.
Reflux esophagitis:
30 mg daily for 4-8 weeks, then 15 mg for maintenance dose. The maintenance dose of GERD can be increased depending on the patient``s response.
Zollinger Ellison syndrome:
60 mg daily to be continued till clinically indicated. Long term clinical experience is limited.

Lansoprazole (Generic Prevacid) - Contraindications

Generic Prevacid is contraindicated in patients with hypersensitivity to lansoprazole or any inactive ingredient of the medication.

Additional Information

Additional Info: Prescribing Information



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