Olanzapine (Zyprexa) - Uses, Dosage and Side Effects

Olanzapine is approved by the FDA for the treatment of schizophrenia and bipolar disorder.

Side Effects of Olanzapine (Zyprexa)

The possible Side effects of Olanzapine (Zyprexa) include akathisia, inability to remain still (restlessness) dry mouth, dizziness, irritability, sedation, insomnia, constipation, urinary retention, orthostatic hypotension, weight gain, increased appetite, runny nose impaired judgment, thinking, and motor skills impaired spatial orientation, impaired responses to senses seizures trouble swallowing dental problems and discoloration of teeth missed periods, problems with keeping body temperature regulated apathy, lack of emotion and Auditory Hallucinations.
Endocrine side effects have included hyperprolactinemia, hyperglycemia, and diabetes mellitus.

Zyprexa TabletsView Of Zyprexa Tablets 10 mg

Olanzapine (Zyprexa) - Dosage

The Dose of Olanzapine may be adjusted depending on the patient's response to the drug as well as the patients medical problems. The dose also will depend on certain the person may have. It is generally recommended to be taken once daily before bed as it is highly sedating. Sedation however tends to diminish as treatment is pursued.
In the case of Schizophrenia in adults the oral dose starts at 5-10 mg once daily(usually taken at night) The dosage is usually increased to 10 mg/day within several days.

Overdosage and Overdose Symptoms of Olanzapine

Symptoms of an overdose include tachycardia, agitation, dysarthria, decreased consciousness and coma. Death has been reported after an acute overdose of 450 mg, but also survival after an acute overdose of 1500 mg.
There is no known specific antidote for olanzapine overdose. Physicians are recommended to call a certified poison control center for information on the treatment of such a case. Prescription should be kept in small quantity to reduce risk overdose as acute bipolar disorder and schizophrenic patients can be at a high risk of suicide.

Olanzapine (Zyprexa) - Availability And Packaging

Olanzapine is available as Generic Zyprexa Tablets (Oleanz manufactured by SUN Pharmaceutical Industries Ltd.) which is packaged in tablets of 10 mg and 20 mg. Olanzapine is also available as a tablet in strengths of 2.5 mg, 5 mg, 7.5 mg, and 15 mg. It also comes as an orally disintegrating wafer (known as Zydis), which dissolves on the tongue. It is also available as a 10 mg vial for a rapid-acting intramuscular injection for short-term acute use. Other trade names include Zalasta, Zolafren, Olzapin, Oferta and Zypadhera.

Additional Information

Additional Info: Prescribing Information



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