Rifaximin Tablets (Rifagut) - Product information and Uses
Rifaximin is a semisynthetic, rifamycin based non-systemic antibiotic that is used for the the treatment or prevention of traveller's diarrhea caused by E. coli. in patients 12 years and above and reduction in risk of overt hepatic encephalopathy (HE) recurrence in patients 18 years of age and above.
Rifaximin Tablets may also be effective in relieving chronic functional symptoms of bloating and flatulence that are common in irritable bowel syndrome. Generic Xifaxan should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Rifaximin Tablets - Availability And Packaging
Rifaximin is available as Rifagut (manufactured by Sun Pharmaceuticals Ltd.) which is packaged in 200 mg and 400 mg Tablets.
Side Effects of Rifaximin Tablets (Rifagut)
The most common side effects of Generic Rifaximin in patients undergoing therapy for travelersâ€™ diarrhea with an incidence rate of 5% or more are Flatulence, headache, abdominal pain, rectal tenesmus, defecation urgency and nausea.
The most common side effects in patients undergoing therapy for overt hepatic encephalopathy (HE) with an incidence rate of 10% or more are Peripheral edema, nausea, dizziness, fatigue, ascites, flatulence, and headache.
Generic Xifaxan - Dosage
The recommended dosage of Rifagut (Generic Rifaximin) for various indications is given below:
Travelersâ€™ diarrhea: One 200 mg tablet taken orally three times a day for 3 days, with or without food
Hepatic encephalopathy: One 550 mg tablet taken orally two times a day, with or without food
Rifaximin Tablets (Rifagut) - Contraindications
Use of Generic Rifaximin tablets is contraindicated in patients with a hypersensitivity to rifaximin, rifamycin antimicrobial agents, or any of the ingredients present in Generic Xifaxan. Hypersensitivity reactions to Rifaximin include exfoliative dermatitis, angioneurotic edema, and anaphylaxis.
Generic Xifaxan should not be used by pregnant women as it may cause fetal harm. Nursing Mothers should discontinue nursing or use of Generic Xifaxan, taking into account the importance of the drug to the mother. Caution should be exercised when Rifaximin Tablets are administered to patients with severe hepatic impairment.
Overdosage and Overdose Symptoms of Rifagut Tablets (Generic Rifaximin)
There is no specific information available on the treatment of overdosage with Rifaximin Tablets. In case of overdose, discontinue Rifaximin, treat symptomatically, and institute supportive measures as required.
Additional Info: Prescribing Information