Terbinafine hydrochloride (Lamisil) - Uses, Dosage and Side Effects

Terbinafine hydrochloride is a synthetic allylamine antifungal. As a 1% cream or powder it is used for superficial skin infections such as jock itch (Tinea cruris), athlete's foot (Tinea pedis) and other types of ringworm (Tinea corporis).
Oral 250mg tablets are often prescribed for the treatment of onychomycosis of the toenail or fingernail due to the dermatophyte Tinea unguium. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts.

Side Effects of Terbinafine hydrochloride (Lamisil)

Below is mentioned a comprehensive list of side effects that are associated with the use of Terbinafine hydrochloride (Lamisil)
Gastrointestinal Problems: Diarrhoea, constipation, nausea, sickness, fullness, abdominal pain, indigestion, dyspepsia, gastritis, cholestasis, flatulence, altered stool colour,abdominal muscular pain.
Central Nervous System / Neurological Problems: Headaches, dizziness, vertigo, light-headedness, decreased concentration levels
Hepatic Problems: Raised liver enzymes, liver inflammation (hepatitis), liver damage, liver failure
Immune System Problems: Decreased white blood cell counts including pancytopenia, leukopenia, lymphopenia, thrombocytopenia, agranulocytosis, and neutropenia. Auto-immune reactions such as lupus erythematosus
Psychological Problems: Depression, anxiety, insomnia, increased / unusual dream activity, malaise.
Sensory Problems: Complete loss of taste (ageusia), decreased taste (hypogeusia) and distorted taste (dysgeusia) often involving a metallic taste sensation and dry mouth. Visual disturbances including blurred vision, green vision and double vision.
Skin Problems: Rash, hives. (urticaria), skin irritation, itching (pruritis), jaundice , Stevens-Johnson syndrome.
Other Problems: Fatigue, increased heart rate (tachycardia), hair loss, decreased red blood cell count (anemia), muscle pain (myalgia), joint pain (arthralagia).
The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests

Terbinafine hydrochloride (Lamisil) - Dosage

Take one tablet of Lamisil 250 mg Once each day for 6 weeks (42 pills) to treat fungal infections of your fingernail, For treating fungal infections of your toenail take 1 tablet each day for 12 weeks (84 pills).
Continue to take the tablets for your full course of treatment even if symptoms improve.

Terbinafine hydrochloride (Lamisil) - Availability And Packaging

Terbinafine hydrochloride is available as Generic Lamisil Tablets which is packaged in tablets of 250 mg. Terbinafine hydrochloride is also available as Generic Lamisil Ointment
Generic lamisil is also sold under the brand name Terbicip (Cipla Ltd.), Sebifin (Ranbaxy Labs), Zimig (GSK Pharma), mycoCeaze (Progres' Laboratories), Zabel, Corbinal and Terbisil

Additional Information

Additional Info: Prescribing Information

Considerable portions of the text here is from http://en.wikipedia.org/wiki/Terbinafine and is reproduced here under the Creative Commons Attribution-ShareAlike License